Avanafil: A serious challenge for Viagra, Cialis and Levitra


avanafil_imageAvanafil is the name for a compound produced by Vivus Inc. It is currently be studied for erectile dysfunction. Avanafil is a prescription drug advertised as a sexual enhancement product for men who may be suffering from erectile dysfunction. The company says this particular product may be far superior to competitors’ drugs.

Avanafil is what is known as a PDE5 (phosphodiesterase type 5) inhibitor. Avanafil works the same way as the three other ED drugs currently on the market: Viagra, Cialis, and Levitra. blocks the activity of a protein that  prevents blood vessels from expanding. Thus allowing blood to enter the penis and become erect during times of sexual excitement. According to the news,  avanafil is better at concentrating its activity on PDE5 than other drugs in its class.

Not much information has been reported about avanafil side effects. In general, the side effects of Phosphodiesterase inhibitors include hypotension, flushing, headache, nasal congestion and heartburn and these effects are dose dependent .

What Latest Study says ?

According to a statement released by the makers, Vivus, on Monday, the speed with which the drug avanafil works has been described as “surprising”. The reign of the record-breaking erectile dysfunction drug, Viagra, is headed for a serious challenge from a new product, which is effective in just 15 minutes — far much faster than the other leading players in the market. “The magnitude of success in the first 15 minutes was surprising. The previously released results demonstrated rapid onset and a long duration of effect,” said Leland Wilson, chief executive officer of Vivus. In order to determine how quickly patients had success with avanafil, explains Wilson, an analysis of the results was performed, which showed efficacy within a quarter of an hour.

The speed with which an impotence drug works is said to be important when consumers are choosing a product. “From our discussions with patients and physicians, we knew that rapid onset was an important attribute in the selection of an ED therapy,” says Dr Charles Bowden, director of Clinical Development at Vivus on the company website. These are some of the most counterfeited medical products in Kenya, with Eli Lilly being forced to change its packaging, because of the trend, a few years ago. Wilson says 72 per cent of sexual acts in the first 15 minutes were successful in the study group.

Dr Bowden quotes a recent study among 1,900 patients with ED, which showed that 75 per cent of patients identified rapid effect as an important treatment expectation. “Knowing that avanafil can be effective within 15 minutes should create an attractive position in the market,” he says.

Read more about Avanafil Study

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